Inovio Appoints Global Commercial Leader to its Board of Directors

3/25/19

Dr. Ann C. Miller

Inovio Pharmaceuticals, Inc. (NASDAQ: INO) announced today the appointment of Dr. Ann C. Miller to its Board of Directors. Dr. Miller had an outstanding marketing career launching and building blockbuster products for Merck, Amgen, Eisai and Sanofi. While at Sanofi, she led the Sanofi Oncology Global Marketing function including its pipeline, launch, and life cycle management activities. Prior to Sanofi, Dr. Miller served as Senior Vice President at Eisai, including leading the Primary Care and Specialty Business unit with the blockbusters Aricept and Aciphex and the enterprise-wide service platform for the Oncology and Primary Care businesses. At Amgen, Dr. Miller contributed to building the Global Marketing function; as Executive Director, Global Marketing, Oncology Therapeutic Area she provided commercialization and life cycle management oversight for key products including Neulasta and Vectibix. During her 16-year career at Merck & Co. she held numerous positions of increasing responsibility including brand lead for such billion-dollar products as Fosamax, Mevacor, and Zocor. Dr. Miller holds MD and BA degrees with honors from Duke University.

Dr. J. Joseph Kim, President and CEO, said, "Dr. Miller's expertise will help guide us as we transition to a commercial organization. We will benefit from her clinical training and extensive experience developing and executing launch and growth strategies across a wide range of oncology, specialty and primary care portfolios and products."

Inovio is in late-stage development for several of its product candidates. Inovio's lead product, VGX-3100, for HPV-caused cervical dysplasia, is advancing in global Phase 3 trials. Inovio is developing its HPV program in Phase 2 trials treating HPV-caused vulvar and anal dysplasia. Inovio's technology platform is demonstrating its versatility in two Phase 2 oncology combination trials integrating Inovio's INO-5401 therapy with several checkpoint inhibitors from Genentech/Roche (for bladder cancer,) and Regeneron (for brain cancer (GBM)). MEDI0457 (VGX-3100 + pIL-12, which Inovio licensed to AstraZeneca) is in Phase 2 combination trials with durvalumab targeting head & neck cancer and cervical cancer in addition to a broad array of other cancers associated with the human papilloma virus. Inovio's infectious disease pipeline is also moving vaccines into late-stage trials for Lassa fever, Ebola, MERS and HIV.

About Inovio Pharmaceuticals, Inc.

Inovio is a late-stage biotechnology company focused on the discovery, development, and commercialization of DNA-based immunotherapies and vaccines that transform the treatment and prevention of cancer and infectious disease. Inovio's proprietary technology platform applies antigen sequencing and DNA delivery to activate potent immune responses to targeted diseases. The technology functions exclusively in vivo, and has been demonstrated to consistently activate robust and fully functional T cell and antibody responses against targeted cancers and pathogens. Inovio's most advanced clinical program, VGX-3100, is in Phase 3 for the treatment of HPV-related cervical pre-cancer. Also in development are Phase 2 immuno-oncology programs targeting HPV-related cancers, bladder cancer, and glioblastoma, as well as platform development programs in hepatitis B, Zika, Ebola, MERS, and HIV. Partners and collaborators include AstraZeneca, Regeneron, Roche/Genentech, ApolloBio Corporation, The Wistar Institute, The Bill & Melinda Gates Foundation, the University of Pennsylvania, Parker Institute for Cancer Immunotherapy, CEPI, DARPA, GeneOne Life Science, Plumbline Life Sciences, NIH, HIV Vaccines Trial Network, National Cancer Institute, Walter Reed Army Institute of Research, Drexel University, and Laval University. For more information, visit www.inovio.com.

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